Synthetic talc prepared using hydrothermal processes (P2, P3 and P4) leads to a product: (1) with a talc-like structure (Figure 7 and Figure 11), (2) with a high chemical …

The ability to measure color value using spectrophotometers allows pharmaceutical companies to accurately detect levels of impurities in talc and other white materials intend for medical purposes and eliminates restriction for use due to errors. This saves both time and money, and allows production to operate smoothly.

This Special Issue is dedicated to in-depth studies presenting fundamental advancement in the scientific field of powder processing in pharmaceutical applications. Contributions address thorough insight into unit operations using model approaches that provide predictions of effects such as overmixing, applied flow characteristics, and …

Nearly 40% of the top 200 oral drugs marketed in the USA and Europe, and 90% of the new chemical entities which are in the drug development pipelines in the pharmaceutical industry, are poorly water-soluble (Tan et al. 2017).Thus, the low solubility of the drug at the site of administration leads to a low quantity of available diffusion, …

This study investigated the influence of excipient composition to the roller compaction and granulation characteristics of pharmaceutical formulations that were comprised of a spray-dried filler (lactose monohydrate or mannitol), pregelatinized starch, talc, magnesium stearate (1% w/w) and a ductile active pharmaceutical ingredient (25% …

A cradle-to-gate assessment considers the production of synthetic talc from different magnesium and reagent acid precursors at different concentrations. The …

The most abundant mineral phase was talc (Table 2) but other minerals also appeared in minor quantities: dolomite, chlorite, quartz, calcite and magnesite, as well as pharmaceutical cosmetic additives such as zincite and hydrozincite.These additives gave the material a more coloured appearance (higher a*, Table 1).The XRD diagrams (Fig. 1) …

Talc is widely used in the pharmaceutical industry due to its unique properties, including its ability to absorb moisture, lubricate, and flow easily. It is commonly used in tablet formulations as a lubricant and diluent, which helps to improve the flow properties of the powder mixture and … See more

literature, talc is used as filler, lubricant and glidant in the pharmaceutical formulations as. well as in cosmetic formulations as abrasive, absorbent, anticaking agent, opacifying agent. and skin protectant. Also, talc is used as a dissolution retardant in the controlled release.

Talc serves as a lubricant in the pharmaceutical industry, preventing the sticking of powders to manufacturing equipment and minimizing wear and tear. This leads to higher production efficiency ...

Innovations in the areas of pharmaceutical technology have contributed to the formulation of the products having superior efficacy as well as other attributes that may contribute to clinical response and patient acceptability. ... Zinc inhibits the production of VSC in the oral cavity by interacting with sulphur in the amino acids or their ...

Talc is a whitish raw material of mineral origin used in the pharmaceutical industry. Talc quality for pharmaceutical uses is regulated by pharmacopoeias, which include several chemical and ...

1. Introduction. The coating has gained tremendous applications in the pharmaceutical industry [[1], [2], [3]], chemical industry, food industry [4, 5], biomedical/biological [6], petroleum [7], and agriculture [8, 9] also.The basic part of the plan is in the pharmaceutical drug dose is to accomplish an exquisite quality such as colour, …

The present review highlights meticulous account of talc with respect to extraction from mines, purification, pharmaceutical and other applications. Talc is a hydrous magnesium silicate having a ...

The technology greatly improved coating production yield and reproducibility, essential for producing high quality medicinal products. Thus, it offers a reliable and scalable industrial solution for the development of sustained-release liquid medicines which could be beneficial for paediatric and older patients who cannot swallow …

A seemingly minor product fault during R&D can become unmanageable during production – when making changes to a formulation is costly and time-consuming. Conducting studies on a formulation during R&D and scale-up can help identify and solve potential powder flow issues before moving into commercial production. Storage …

These solid dosage forms are used to administer medicine through the rectum (suppositories) and the vagina or urethra (inserts). They melt, soften, or dissolve in the body cavity. Rectal suppositories are cylindrical or conical and are tapered or pointed at one end. They generally weigh approximately 2 g and are about 1 to 1.5 inches long. …

Introduction. Numerous authors have sought to categorize the various methods corporations use to influence scientific research, government regulation, and public discourse in an effort to avoid regulation. 1 –8 These methods rely on industry connections to and influence on regulatory agencies. They often include the production, …

J R DrugChem Pvt Ltd is a leading manufacturer of Pharmaceutical Excipients. With more than 25 years of experience and expertise, we manufacture and provide high quality Active Pharmaceutical Ingredients (APIs) and Excipients that are essential for the production of safe and effective medicines.

The association has an established tradition of research and information in its main areas of interest: EUROTALC's membership extends to over nine EU producing countries and covers more than 95% of EU talc production. EUROTALC is a member of IMA-Europe, the European industrial minerals association. EUROTALC is a comprehensive source of ...

1. 1gm of ethyl cellulose/ or cellulose acetate was accurately weighed. 2. 30ml of acetone was added. 30min. 4. Added 0.5gm of magnesium sterate, continue stirring for 10min. 5. 50ml of liquid ...

Talc can be produced by hydration and carbonation of various minerals. Talc demonstrates the high functionality because it has been used as filler, lubricant and …

technology of pharmaceutical talc production. technology of pharmaceutical talc production. Talc which is a clay mineral is found in many locations throughout the world Many countries actually use talc production as a major source of export capital Talc is found in a variety of forms which gives talc its economic . » Learn More. Containment

Pharmaceutical technology technicians are called upon to take part in production planning and configure manufacturing processes of varied dosage forms. They also carry out in-process testing and intervene in emergency situations. These technicians work as part of multidisciplinary teams regulated by Health Canada's Good Manufacturing ...

Optimization methodologies can greatly aid the production of pharmaceutical products by providing a systematic framework to process improvement. ... Optimization of tablet formulations containing talc. Drug Dev Ind Pharm 17(10):1343–1371 ... Optimization methods, in encyclopedia of pharmaceutical technology. Informa Healthcare, England ...

Being an excellent excipient for tablets and carrier for medicated powders and a glidant and lubricant in tablet production, Talc is widely used for these purposes in the parhma industry. Talc acts as an excellent anti …

World production of talc and pyrophyllite in both 2003 and 2004 was estimated to be 8.3 million tonnes. Of the total production, approximately 2.15 million tonnes were confirmed to be used for talc production in both 2003 and 2004. China was the leading producer of talc in the world, followed by the USA, India, Brazil (crude) and France (crude).

This review delivers a brief review on film coating in solid dosage form, which includes tablets, with a focus on the polymers and processes used in the coating. At the end, some pharmaceutical applications were also discussed. Keywords: solid dosage form, uniformity in coating process, tablets, polymers, and film coating.

Emerging Technology for Modernizing Pharmaceutical Production. T. O'Connor, S. Lee, in Developing Solid Oral Dosage Forms (Second Edition), 2017 37.6 Conclusion. Continuous pharmaceutical manufacturing offers potential flexibility, quality, and economic advantages over batch processing, both in process development and …

2. Talc is used as mineral filler in various industries to reduce production cost and/or gain new properties. As example, for its high thermal stability, talc is used as a refractory material in kiln furniture; for its neutral electric charge, it is used as an electrical and thermal insulator material in composites. For its platy shape,

Six pharmaceutical pastes were prepared using chemically modified kaolin and talc powders. Tests were conducted to determine their structural and chemical characteristics as well as their antimicrobial protection, thus rendering them suitable for cosmetic and pharmaceutical uses. Kaolin and talc were treated chemically via the …

This article focuses on the use of additives and processing aids in excipients with established safety profiles and precedence of use and the concerns with compliance …

and domestic production of crude talc was estimated to be nearly unchanged at 580,000 tons valued at $26 million. Talc was mined in Montana, Texas, and Vermont. Total sales (domestic and export) of talc by U.S. producers were estimated to be 560,000 tons valued at about $180 million. Talc produced and sold in the United States was used in

A perfect active pharmaceutical ingredient is one that performs well from R&D through tablet production. However, in real-world situations challenges are inevitable. Here, Jonathan Gaik, director, Natoli Scientific, looks at the critical issue of powder flow and how solving issues before production can reduce product performance issues later ...

Introduction. This chapter provides background information to support Detection of Asbestos in Pharmaceutical Talc 〈901〉. It describes analytical procedures for X-ray diffraction (XRD)—also termed X-ray powder diffraction (XRPD)—and polarized light microscopy (PLM), both of which can be effective for testing of asbestos in talc. Some of ...

Introduction. Production technology is a broad term that refers to the use of advanced technologies to improve the production process. It encompasses a range of techniques such as automation, robotics, and manufacturing technologies. By leveraging these technologies, businesses can increase efficiency, reduce costs, and improve quality.

The leading use of talc in the United States is in the production of ceramics, where it is a source of magnesium oxide, serves as a flux to reduce firing temperatures, and improves thermal shock characteristics of the final product. ... asphalt shingles, window caulk, wallboard joint compound, pharmaceutical tablets, chewing gum, candy, gaskets ...

examined the flow behavior of acetaminophen, didesmethylesibutramine tartarate, and levalbuterol tartrate after mixing with lubricants colloidal silica, talc, and …

The chief problem of the pharmaceutical formulation of a biological active molecule is to retain its therapeutic activity level at the desired site of action and for the specific time period. Sterilization of pharmaceutical drug substance, as well as excipients, must be required to avoid microbiological contamination (Reineke et al., 2015). For ...